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9781617792465 - Humana Press: Cancer Stem Cells in Solid Tumors
1
Humana Press (?):

Cancer Stem Cells in Solid Tumors (2015) (?)

Delivery from: Netherlands

ISBN: 9781617792465 (?) or 1617792462, in english, Humana Press, New, ebook

£ 198.22 ( 225.29)¹(without obligation)
Direct beschikbaar
bol.com
The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and E... The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requirement for a specific “niche”/microenvironment to grow; and an increased capacity for self-protection against harsh environments, toxins, and drugs. Cancer Stem Cells in Solid Tumors represents a detailed overview of cancer stem cells and their role in solid cancers. Comprised of 24 chapters, this volume will provide readers with a comprehensive understanding of this important and evolving field. Topics covered include:Introduction of the CSC hypothesisHistorical perspectives and the contributing lessons from leukemiaCurrent knowledge regarding the identification and role of CSCs in various forms of solid cancer including breast, brain, colorectal, pancreatic, prostate, melanoma, lung, ovarian, hepatocellular, and head and neck cancer Molecular pathways involved in driving CSC function, with a particular focus on the novel convergence of embryonic and tumorigenic signaling pathways In vitro and in vivo assays, model systems, and imaging modalities for studying CSCsThe clinical importance of CSCs for cancer management and treatment, including important implications for prognosis, prediction, and treatment resistanceConsideration of the controversy surrounding the CSC hypothesis and important unanswered questions in this field This collective work was written by a group of prominent international experts in cancer biology, oncology, and/or stem cell biology. It will serve as a valuable resource for established researchers, professors, health care professionals, and students in the medical and scientific community who are investigating stem cells and/or oncology.Taal: Engels;Formaat: ePub met kopieerbeveiliging (DRM) van Adobe;Kopieerrechten: Het kopiëren van (delen van) de pagina's is niet toegestaan ;Geschikt voor: Alle e-readers te koop bij bol.com (of compatible met Adobe DRM). Telefoons/tablets met Google Android (1.6 of hoger) voorzien van bol.com boekenbol app. PC en Mac met Adobe reader software;Verschijningsdatum: september 2015;ISBN10: 1617792462;ISBN13: 9781617792465; Engelstalig | Ebook | 2015
9781617792465 - Alison L. Allan: Cancer Stem Cells in Solid Tumors
2
Alison L. Allan (?):

Cancer Stem Cells in Solid Tumors (2011) (?)

ISBN: 9781617792465 (?) or 1617792462, in english, Humana Press, Humana Press, Humana Press, New, ebook, digital download

£ 229.29 ( 260.61)¹(free shipping, without obligation)
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The "cancer stem cell" hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requirement for a specific "niche"/microenvironment to grow; and an increased capacity for self-protection against harsh environments, toxins, and drugs. Cancer Stem Cells in Solid Tumors represents a detailed overview of cancer stem cells and their role in solid cancers. Comprised of 24 chapters, this volume will provide readers with a comprehensive understanding of this important and evolving field. Topics covered include: Introduction of the CSC hypothesisHistorical perspectives and the contributing lessons from leukemiaCurrent knowledge regarding the identification and role of CSCs in various forms of solid cancer including breast, brain, colorectal, pancreatic, prostate, melanoma, lung, ovarian, hepatocellular, and head and neck cancer Molecular pathways involved in driving CSC function, with a particular focus on the novel convergence of embryonic and tumorigenic signaling pathways In vitro and in vivo assays, model systems, and imaging modalities for studying CSCsThe clinical importance of CSCs for cancer management and treatment, including important implications for prognosis, prediction, and treatment resistanceConsideration of the controversy surrounding the CSC hypothesis and important unanswered questions in this field This collective work was written by a group of prominent
9781617792465 - Cancer Stem Cells in Solid Tumors
3

Cancer Stem Cells in Solid Tumors (?)

ISBN: 9781617792465 (?) or 1617792462, in english, New

£ 0.00 (Spr 229.00)¹(free shipping, without obligation)
In Stock
From Seller/Antiquarian
Allan, Cancer, Cell, Solid, Stem, Tumor, Life Sciences; Stem Cells; Cell Biology; Cancer Research